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In mismatch repair system of eukaryotes, the gap between Okazaki fragments can be used for MutH binding and its hydrolysis of mismatch site.()

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MutS in mismatch repair system can recognize mismatch sites of nascent strands by specific sequences.()

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Which of the following point mutation can affect the sequence of polypeptide:()

A. silent mutation
B. missense mutation
C. non-sense mutation
D. Insertion
E. deletion

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Which of the following change is transversion:()

A → G
B. T → G
C. A → T
D. C → G
E. C → T

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Knocking out the kinase A of mouse can lead to its death in embryonic period, then which of the following mutation of the sequence encoding kinase A most likely lead to the death of mouse:()

A. adenine replaces cytosine
B. cytosine replaces guanine
C. methylcystein replaces cytosine
D. loss of three nucleotides
E. insertion of one nucleotide

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