Which of the following point mutation can affect the sequence of polypeptide:()
A. silent mutation
B. missense mutation
C. non-sense mutation
D. Insertion
E. deletion
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Which of the following change is transversion:()
A → G
B. T → G
C. A → T
D. C → G
E. C → T
Knocking out the kinase A of mouse can lead to its death in embryonic period, then which of the following mutation of the sequence encoding kinase A most likely lead to the death of mouse:()
A. adenine replaces cytosine
B. cytosine replaces guanine
C. methylcystein replaces cytosine
D. loss of three nucleotides
E. insertion of one nucleotide
Sickle cell anemia is the homozygote genotype of abnormal hemoglobin. β-strand aberrance is caused by which of the following mutations:()
A. chromosome arm exchange
B. mononucleotide insertion
C. mononucleotide loss
D. chromosome nondisjunction
E. base substitution
The Dam methylase in E. coli can methylate the A of GATC sequence in DNA. Which of the following is unrelated to this modification:()
A. Protein SeqA can inhibit the methylation of GATC by Dam
B. The marker of DNA parental strand after replication
C. The full-methylated sequence GATC is the binding site of initiator protein DnaA
D. The methylation site is recognition site of MutH in mismatch repair system
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