题目内容

MutS in mismatch repair system can recognize mismatch sites of nascent strands by specific sequences.()

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Which of the following point mutation can affect the sequence of polypeptide:()

A. silent mutation
B. missense mutation
C. non-sense mutation
D. Insertion
E. deletion

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Which of the following change is transversion:()

A → G
B. T → G
C. A → T
D. C → G
E. C → T

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Knocking out the kinase A of mouse can lead to its death in embryonic period, then which of the following mutation of the sequence encoding kinase A most likely lead to the death of mouse:()

A. adenine replaces cytosine
B. cytosine replaces guanine
C. methylcystein replaces cytosine
D. loss of three nucleotides
E. insertion of one nucleotide

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Sickle cell anemia is the homozygote genotype of abnormal hemoglobin. β-strand aberrance is caused by which of the following mutations:()

A. chromosome arm exchange
B. mononucleotide insertion
C. mononucleotide loss
D. chromosome nondisjunction
E. base substitution

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