Single-strand binding protein in the replication fork can separate two strands of DNA and prevent the complementary pairing of bases.()
In the process of DNA replication, the leading strand is synthesized in the direction of 5’→3’, while the lagging strand in the direction of 3’→5’.()
When DNA topoisomerase II in yeast is mutated, DNA replication process would not be affected, but its chromosome cannot be separated in the process of mitoses.()
Which of the following is correct about the Okazaki fragment:()
A. It is synthesized by DNA polymerase
B. It is the discontinuous fragment in the lagging strand.
C. It is synthesized in the direction of 3’→5’.
D. It has free 3’-OH end.