Which is the modification of lysines in histone:()
A. Methylation
B. Acetylation
C. Phosphorylation
D. Ubiquitylation
E. Sumoylation
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Which modification is associated with activation of chromatin:()
A. Methylation of H3K4
B. Acetylation of H3K9
C. Acetylation of H3K14
D. Methylation of H3K27
E. Methylation of H3K9
In most cases, which kind of modification would inhibit the expression of gene:()
Acetylation of histone
B. Methylation of CpG island
C. Sumoylation of histone
D. Phosphorylation of histone
Which is correct in following statement:()
A. Gene expression can be found only when the gene is completely methylated.
B. Usually a gene can be expressed when its promoter is non-methylated.
C. The methylation of DNA can changed along with the development state of the cell.
D. After replication of DNA,DNMT can recognize the semi-methylated site and make nascent DNA methylated to ensure the methylation of the genome.
In the following statement of the histone modification, which is NOT correct:()
A. The methylation of histone is usually the signal of silence gene, while the highly methylated gene is usually inactivated.
B. The modification of histone terminal is the switch of gene activation and inactivation.
C. The acetylation of histone can only activate the gene expression, while the deacetylation of histone can only inhibit the gene expression
D. The phosphorylation of histone can usually activate a gene, thus promote the gene expression
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