In most cases, which kind of modification would inhibit the expression of gene:()
Acetylation of histone
B. Methylation of CpG island
C. Sumoylation of histone
D. Phosphorylation of histone
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Which is correct in following statement:()
A. Gene expression can be found only when the gene is completely methylated.
B. Usually a gene can be expressed when its promoter is non-methylated.
C. The methylation of DNA can changed along with the development state of the cell.
D. After replication of DNA,DNMT can recognize the semi-methylated site and make nascent DNA methylated to ensure the methylation of the genome.
In the following statement of the histone modification, which is NOT correct:()
A. The methylation of histone is usually the signal of silence gene, while the highly methylated gene is usually inactivated.
B. The modification of histone terminal is the switch of gene activation and inactivation.
C. The acetylation of histone can only activate the gene expression, while the deacetylation of histone can only inhibit the gene expression
D. The phosphorylation of histone can usually activate a gene, thus promote the gene expression
The direct methyl donor for the methylation of DNA in vivo is:()
A. Met
B. S-adenosyl methionine
C. Formylmethionine
D. Met-tRNA
Both the transcriptional activator and transcriptional co-activator can activate the transcription process, the difference between these two is whether it would bind to the DNA.()
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