Q9 – A bacterium carries an antibiotic resistance gene on a plasmid. We program a CRISPR-Cas9 system to target this gene. What happens?
A. 1 - The bacteria dies.
B. 2 - A mutation is introduced in the target gene.
C. 3 - The plasmid carrying the target gene is lost.
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Q10 – You want to block the expression of a target gene using dCas9. Which of the following options is a poor design choice?
A. 1 - Targeting the promoter of the gene.
B. 2 - Targeting the template strand of the gene.
C. 3 - Targeting the coding strand of the gene.
Q1– Among the following specialists, which ones are usually not involved in the antibiotic stewardship team?
A. 1 - Clinical microbiologists.
B. 2 - Pathologists.
C. 3 - Community health workers.
D. 4 - Infectious diseases specialists.
E. 5 - Pharmacists.
Q2 – What are the main activities of antibiotic stewardship teams?
A. 1 - Give recommendations on appropriate use of antibiotics agents.
B. 2 - Give recommendations on behavioral change on the use antibiotics.
C. 3 - These two activities constitute the main missions of the antibiotic stewardship team.
Q1 - Among the following options, which one is NOT correct? Carbapenemase-producing Enterobacteriae (CPE) should be targeted as one of the most critical, multidrug-resistant organism in healthcare facilities because:
A. 1 - Carbapenemase-producing Enterobacteriae infections cause high morbidity/mortality.
B. 2 - Carbapenemase-producing Enterobacteriae belong to the saprophytic flora.
C. 3 - Carbapenemase-producing Enterobacteriae represent a stable mechanism of resistance.
D. 4 - Carbapenemase-producing Enterobacteriae can show a prolonged carriage.
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