题目内容

Drugs that are highly bound to albumin:( )

A. Effectively cross the BBB
B. Are easily filtered at the glomerulus
C. Have a large Vd
D. Often contain quaternary nitrogens
E. Can undergo competition with other drugs for albumin binding sites

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If a drug is known to be distributed into total body water, what dose () is needed to obtain an initial plasma level of 5 mg/L in a patient weighing 100 kg?( )

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