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Which of the following is a phase II drug metabolism reaction associated with a genetic polymorphism? ( )

Acetylation
B. Glucuronidation
C. Oxidation
D. Reduction
E. Glutathione conjugation

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A 300-mg dose of a drug has therapeutic efficacy for 6 h. If the half-life of the drug is 8 h, for how long would a 1200mg dose be effective? ( )

A. 12 h
B. 16 h
C. 18 h
D. 20 h
E. 22 h

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An example of an agent that exerts much of its effects through intracellular receptors that in complex form binds to DNA response elements: ( )

A. acetylcholine
B. dopamine
C. corticosteroids
D. diltiazem
E. atropine

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Two most important sites for drug elimination: ( )

A. pulmonary and liver
B. liver and gastrointestinal tract
C. kidney and liver
D. skin and liver
E. pulmonary and kidney

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Which bacterial process() do quinolones and fluoroquinolones inhibit? ( )

A. DNA synthesis.
B. RNA synthesis.
C. DNA synthesis and RNA synthesis.
D. Quinolones and fluoroquinolones do not affect nucleic acid synthesis.
E. FH2 reductase

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Which of the following is a phase II drug metabolism reaction associated with a genetic polymorphism? ( )

Acetylation B. Glucuronidation C. Oxidation D. Reduction E. Glutathione conjugation

A 300-mg dose of a drug has therapeutic efficacy for 6 h. If the half-life of the drug is 8 h, for how long would a 1200mg dose be effective? ( )

An example of an agent that exerts much of its effects through intracellular receptors that in complex form binds to DNA response elements: ( )

Two most important sites for drug elimination: ( )

Which bacterial process() do quinolones and fluoroquinolones inhibit? ( )

Acetylation
B. Glucuronidation
C. Oxidation
D. Reduction
E. Glutathione conjugation