Both the transcriptional activator and transcriptional co-activator can activate the transcription process, the difference between these two is whether it would bind to the DNA.()
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In helix-turn-helix motif, recognition helix can interaction with DNA backbone to enhance the force of location and combination.()
In leucine zipper motif, leucine appears in every 7 amino acids, and it combine to DNA via these leucines of the structure.()
In the transcription factor which contains helix-loop-helix motif,its DNA binding domain usually contains more acidic amino acid.()
All of the transcription factors can bind to the basical transcriptional apparatus to initiate the transcription.()