题目内容

Which statement is not true?

All second messengers are water-soluble and diffuse freely through the cytosol.
B. In the regulation of molecular switches, protein kinases and guanine nucleotide exchange factors (GEFs) always turn proteins on, whereas protein phosphatases and GTPase-activating proteins (GAPs) always turn proteins off.
C. Most intracellular signaling pathways provide numerous opportunities for amplifying the responses to extracellular signals.
D. Protein tyrosine phosphatases display exquisite specificity for their substrates, unlike most serine/threonine protein phosphatases, which have rather broad specificity.

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