Acidification of urine increases ionization of weak bases ，and increases renal elimination
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The higher the therapeutic index, the safer the drug
Which neuronal pathway is degeneration with which Parkinsonism is associated ? ( )
A. The reticular formation
B. The mesolimbic dopamine pathway
C. The mesocortical dopamine pathway
D. The nigrostriatal dopamine pathway
E. tubero-infundibular system dopamine pathway
Which factor is the major cause for the recurrence of peptic ulcer? ( )
Acid
B. Pepsin
C. Bile acid
D. Prostaglandins
E. H.pylori
Resistance to β lactams ( )
A. Can be due to an efflux pump
B. Does involve penetration of drug to target PBPs
C. Infers resistance only to penicillin
D. Can involve up to 5 different β-lactamases
E. Can produce modification enzymes
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