Resistance to β lactams ( )
A. Can be due to an efflux pump
B. Does involve penetration of drug to target PBPs
C. Infers resistance only to penicillin
D. Can involve up to 5 different β-lactamases
E. Can produce modification enzymes
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A woman is taking oral contraceptives (). Which of the following drugs is unlikely to reduce the effectiveness of the OCs? ( )
A. Carbamazepine
B. Phenytoin
C. Ketoconazole
D. Phenobarbital
E. Rifampin
At 6 h after IV administration of bolus dose, the plasma level of a drug is 5 mg/L. If the Vd = 20 L and the elimination half-life = 3 h, what was the dose ( ) administered?
A. 100 mg
B. 200 mg
C. 300 mg
D. 400 mg
E. 500 mg
The first choice antihypertensive drugs do not include ( )
A. Thiazide diuretics
B. β-adrenoceptor blocker
C. ACE inhibitors
D. Peripheral α-1 adrenergic antagonists
E. Calcium channel blockers
All of the followings can be treated by benzodiazepines EXCEPT ( )
A. Schizophrenia
B. Seizures
C. Tetanus
D. Insomnia
E. Anxiety