HDAC can further recruit chromatin remodeling complex by acetylation of histone.()
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DNA methylation leads to the change of its conformation, thus inhibit the combination of the transcription factor and the promoter.()
CpG island is a cluster of CpG in the DNA sequence. CpG island in promoter is usually methylated when the gene is activated.()
Which is the modification of lysines in histone:()
A. Methylation
B. Acetylation
C. Phosphorylation
D. Ubiquitylation
E. Sumoylation
Which modification is associated with activation of chromatin:()
A. Methylation of H3K4
B. Acetylation of H3K9
C. Acetylation of H3K14
D. Methylation of H3K27
E. Methylation of H3K9