Which of the following catalyze the synthesis of mRNA in eukaryotic cell:()
A. RNA polymerase I
B. RNA polymerase II
C. RNA polymerase III
D. RNA polymerase core enzyme
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Which is wrong description about promoter:()
A. It is located upstream a gene.
B. The promoter of prokaryotic cells is recognized and combined by RNA polymerase, while the promoter of eukaryotic cells is recognized by general transcription factors.
C. There are some conservative sequences in the promoter region.
D. Both prokaryotes and eukaryotes have promoters.
E. Genes encoding proteins all have the same core promoter factors.
Which of the following statement about transcriptional regulation element is NOT correct:()
A. The general transcriptional factors always bind to core promoter element.
B. Enhancer can be recognized and combined by some transcriptional activation factors.
C. Silencer which also belongs to transcriptional regulatory factors can be combined by transcription inhibitors.
D. TFIID factor can recognize several elements of the core promoter at the same time.
E. The elements in the core promoter functions independently, without synergistic activation between each other.
Which is NOT true about RNA polymerases in eukaryotic cell:()
A. There are at least three RNA polymerases including I, II, III in eukaryotes.
B. RNA polymerase I has the highest transcriptional activity in eukaryotic cells
C. RNA polymerase I is located in the nucleolus, while RNA polymerase II, III are located in nucleoplasm
D. The RNA polymerase II is responsible for the transcription of rRNA genes
E. RNA polymerase III is responsible for the synthesis of precursors of the 5S rRNA, tRNA and other intracellular small RNAs
In gene expression regulation of eukaryotes, which of the following regulatory element can inhibit the transcription:()
A. Enhancer
B. Silencer
C. Promoter
D. Upstream activation sequences
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