题目内容

Which is correct about the mRNA transcription in eukaryotic cells:()

A. The mRNA can contain coding sequences of several proteins.
B. The generation of the 3 'end depends on polyadenylation signal sequence.
C. The 5 'end of mRNA will be capped after the termination of transcription.
D. After mRNA is synthesized and released, RNA polymerase II will still be able to continuously move forward on the DNA template and synthesize another RNA molecule.

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Which of the following process is associated with the phosphorylation in CTD domain of RNA polymerase II:()

A. Degradation of mRNA
B. Splicing of mRNA
C. Termination of mRNA synthesis
D. Modification of the mRNA 5’ end
E. Transfer of mRNA

Which is correct about DNA polymerase and RNA polymerase:()

A. RNA polymerases use nucleoside diphosphate instead of nucleoside triphosphate for synthesis of polynucleotide chains
B. RNA polymerases need primer and add nucleotides in the 5 'end of the polynucleotide chain
C. DNA polymerase can add nucleotides in both ends of the polynucleotide chain
D. All of the RNA polymerases and DNA polymerases can only add nucleotides in the 3’ end of the polynucleotide chain

Which is NOT true about the mediator complex:()

A. It is a necessary component of basal apparatus.
B. Mediator complexe can be connected with many transcription factors, while it does not directly connected with RNA polymerase.
C. The inactivation of a subunit of mediator complex can lead to the abortion of some genes expression.
Different subunits in mediator complex can response to different kinds of transcription factors.

Which of the following statement is NOT true about the transcription initiation of eukaryotes:()

A. General transcription factor are located at promoter by recruiting RNA polymerase II, which can effective initiate most of gene transcription.
B. The components of mediator complex that are necessary for the transcription initiation in eukaryotes may be different.
C. The CTD domain of RNA polymerase II would be phosphorylated in multiple sites in the initiation of transcription.
D. The combination of TFIIB factor and DNA determines the direction of transcription initiation complex.

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