Which is correct about DNA polymerase and RNA polymerase:()
A. RNA polymerases use nucleoside diphosphate instead of nucleoside triphosphate for synthesis of polynucleotide chains
B. RNA polymerases need primer and add nucleotides in the 5 'end of the polynucleotide chain
C. DNA polymerase can add nucleotides in both ends of the polynucleotide chain
D. All of the RNA polymerases and DNA polymerases can only add nucleotides in the 3’ end of the polynucleotide chain
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Which is NOT true about the mediator complex:()
A. It is a necessary component of basal apparatus.
B. Mediator complexe can be connected with many transcription factors, while it does not directly connected with RNA polymerase.
C. The inactivation of a subunit of mediator complex can lead to the abortion of some genes expression.
Different subunits in mediator complex can response to different kinds of transcription factors.
Which of the following statement is NOT true about the transcription initiation of eukaryotes:()
A. General transcription factor are located at promoter by recruiting RNA polymerase II, which can effective initiate most of gene transcription.
B. The components of mediator complex that are necessary for the transcription initiation in eukaryotes may be different.
C. The CTD domain of RNA polymerase II would be phosphorylated in multiple sites in the initiation of transcription.
D. The combination of TFIIB factor and DNA determines the direction of transcription initiation complex.
What is the transcriptional elongation factor of eukaryotic cells:()
A. TFIID
B. TFIIH
C. GRE
D. TFIIS
Which is NOT correct about the transcription process of eukaryotic cells:()
A. RNA polymerase can synthesis RNA only when DNA exists.
B. NTPs are the substrates.
C. The direction of RNA chain is 3' -> 5'.
D. The bases of nascent RNA form complementary base-pairing with bases of DNA molecule.
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