Q4 – What is a Target Product Profile?
A. 1 - The list of competitor compounds with their associated profiles.
B. 2 - The description of the molecular target to be modulated.
C. 3 - The list of clinical indications and properties a Project Team Target has to reach at Candidate stage.
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Q5 – Among the following options, which one is correct? Anti-virulence drugs:
A. 1 - Are likely to have increased therapeutic effects compared to antibiotics.
B. 2 - Are likely to be active in monotherapy compared to antibiotics.
C. 3 - Are likely to be more easily administered before pathogen identification compared to antibiotics.
D. 4 - Are theoretically active in immunocompromised patients compared to antibiotics.
Q6 – Among the following compounds, which one can be used as anti-virulence drugs?
A. 1 - Monoclonal antibodies.
B. 2 - Immunoglobulins.
C. 3 - Antibiotics.
D. 4 - Small RNAs.
E. 5 - All of them.
Q8 - Is phage therapy independent from the immune response?
A. 1 - Yes.
B. 2 - No.
Q9 – A bacterium carries an antibiotic resistance gene on a plasmid. We program a CRISPR-Cas9 system to target this gene. What happens?
A. 1 - The bacteria dies.
B. 2 - A mutation is introduced in the target gene.
C. 3 - The plasmid carrying the target gene is lost.
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