The pharmacological basis of phentolamine in treatment of intractable heart failure mainly is()
A. Excite heart and increase cardiac output
B. Inhibit heart and dilate blood vessels
C. Inhibit heart and decrease myocardial consumption of oxygen
Dilate peripheral vein and reduce cardiac preload
E. Dilate peripheral artery and reduce cardiac afterload
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In low dosage (50-100mg/d) aspirin is responsible for treatment of()
A. Pain
B. Fever
C. Rheumatoid arthritis
D. Thrombosis
E. Headache
The main adverse effects of Phenytoin in children is()
A. Granulocytopenia
B. Vomiting
C. Ataxia
D. Lethargy
E. Gingival hyperplasia
Which of the following types of the administration route is most likely to appear first pass elimination?()
A. intramuscular injection
B. inhalation administraion
C. oral administration
D. Intravenous injection
E. subcutaneous injection
About hife life (first-order elimination kinetics), which is the wrong?()
A. It is the time taken for the plasma concentration of drug to reduce by 50%
B. It could reflect the elimination rate
C. The dosing interval may be adjusted in accordance with hife life
D. It is related to plasma concentration
E. The drug will be eliminated completely after about 4 to 5 half life
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