Q1 - What happens when Cas9 is programmed to target a gene in the chromosome of bacteria?
A. 1 - The target gene is silenced.
B. 2 - The bacteria die.
C. 3 - The target gene is mutated.
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Q2 – What is the protospacer adjacent motif (PAM)?
A. 1 - A small sequence motif identified by Cas9 next to the target sequence.
B. 2 - A small sequence motif on the guide RN
C. 3 - A region in the Cas9 protein.
Q1 – Which of the following answers applies to “old antibiotics”?
A. 1 - They were marketed before 1950.
B. 2 - They are antibiotics that are no longer available in the market.
C. 3 - They are the only antibiotics that remain active for the treatment of infections due to extensively drug resistant (XDR) isolates.
Q2 – Among the following options, which one is not correct? Old molecules could be used for treatment of infection in:
A. 1 - Extended-Spectrum ?-Lactamase producing Enterobacteriaceae.
B. 2 - Multidrug-resistant bacteria.
C. 3 - Pan drug-Resistant bacteria.
Q3 – Which one of these assertions is correct?
A. 1 - Antibacterial agents mostly originate from Natural Products.
B. 2 - High throughput screenings readily yield novel antibacterial hits.
C. 3 - Antibacterial agents are less polar and more hydrophobic than oral drugs.
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