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In pH=5.0 solution, a weak acid drug dissociates about 50%, the pKa value is ( )

A. 4
B. 5
C. 6
D. 7
E. 8

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If t1/2 of certain drug is 8 hours, according to the first order elimination kinetics, the time required to reach steady state is about ( )

A. 8 hours
B. 16 hours
C. 24 hours
D. 40 hours
E. 50 hours

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You need to gradually reduce the amount of propranolol after you take for a long time to treat hypertension before switching to other medications. This is to avoid ( ).

A. side reaction
B. toxic reaction
C. residual effect
D. withdrawal reaction
E. allergic reaction

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One of the following receptors is a ligand-gated ion channel ( ).

A. M receptor
B. GABAB receptor
C. N receptor
D. mGluRs
E. D1 receptor

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The feature of agonist is with ( ).

A. low receptor affinity, α ＝ 1
B. low receptor affinity, α ＝ 0
C. high receptor affinity, α ＜ 1
D. high receptor affinity, α ＝ 0
E. high receptor affinity, α ＝ 1

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In pH=5.0 solution, a weak acid drug dissociates about 50%, the pKa value is ( )

A. 4 B. 5 C. 6 D. 7 E. 8

If t1/2 of certain drug is 8 hours, according to the first order elimination kinetics, the time required to reach steady state is about ( )

You need to gradually reduce the amount of propranolol after you take for a long time to treat hypertension before switching to other medications. This is to avoid ( ).

One of the following receptors is a ligand-gated ion channel ( ).

The feature of agonist is with ( ).

A. 4
B. 5
C. 6
D. 7
E. 8