The feature of agonist is with ( ).
A. low receptor affinity, α ＝ 1
B. low receptor affinity, α ＝ 0
C. high receptor affinity, α ＜ 1
D. high receptor affinity, α ＝ 0
E. high receptor affinity, α ＝ 1
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If the value of pD2 is greater, it means that ( ).
A. the affinity between drug and receptor is stronger, the dose of drug used in the experiment is larger
B. the affinity between drug and receptor is stronger, the dose of drug used in the experiment is smaller
C. the affinity between drug and receptor is weaker, the dose of drug used in the experiment is smaller
D. the affinity between drug and receptor is weaker, the dose of drug used in the experiment is larger
E. the affinity between drug and receptor can not be compared
The therapeutic index is ( ).
A. the ratio of ED90/LD10
B. the ratio of ED95/LD5
C. the ratio of LD50/ED50
D. the distance between ED50 and LD50
E. the ratio of ED50/LD50
The following statement about antihyperlipidemic drugs are correct except that ( )
A. The statins are HMG-CoA reductase inhibitors
B. Niacin primarily reduces LDL and TC
C. Fibrates primarily reduce VLDL and TG
D. Bile acid-binding resins primarily reduce LDL and TC
E. The statins may induce rhabdomyolysis
The mechanism of action of nitroglycerin is related to
A. potassium channel blockade
B. beta-receptor blockade
C. sodium channel blockade
D. calcium channel blockade
E. NO release
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