Coding sequence of microRNAs may be present in the introns of split gene, and it can also exist in the intergenic non-coding regions.()
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Small RNA molecules produced endogenously are called microRNAs, small RNAs that are transformed into cell exogenously are called siRNA.()
A lot of genes can be regulated by one kind of miRNA, some of which are degraded under the regulation of miRNA, while the translation of some genes are only be inhibited.()
Which of the following statement about the initiation of translation in eukaryotes is NOT correct:()
A. During the translation initiation process of eukaryotes, some initial factors binds to the small subunit of ribosome and some factors binds to 5 ' end cap of mRNA.
B. Translation initiation factors may be modified by a variety of intracellular kinases and phosphatases, which would affect the efficiency of translation initiation.
C. During the translation initiation process of eukaryotes, the correct pairing of initiator tRNA and the start codon will lead to the release of various initiation factors.
D. Phosphorylation of eIF2 in eukaryotic cells would strengthen the interaction of eIF2 and eIF2B, contributing to improve the efficiency of translation initiation.
Which of the following statement about microRNA is NOT correct:()
A. Most miRNA will be separately located in the genome, only a few appear in cluster.
B. Each miRNA may target several genes, but the same gene is regulated only by one miRNA.
C. The sequence of miRNA is highly conservative in different species.
D. The regulation of translation process by miRNA relys on RNA-induced silencing complex (RISC).
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