题目内容

In the modification of histone, Bromo domain can recognize:____

A. The acetylation site of histone.
B. The methylation site of histone.
C. The histone terminal that are not modified.
D. Non-histone.

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What’s the following is correct about the loop model:____

A. It is formed by the further folding of 10nm solenoidal fiber.
B. The central axis of loop model consists of non-histones.
C. 16 loops are connected with non-histone and radially arranged in a plane, which forms a micro-strip.
D. About 108 micro-strips are included in a chromatid.

What’s the following statement about the effect of modification in histone terminal on nucleosome stability is NOT correct:____

A. The positive charged amino acid residues in histone terminal benefit for the stable connection of histone and DNA.
B. The acetylation of Lys residue in histone terminal make the packaging of 10nm fiber more closer.
C. The phosphorylation of histone terminal reduces its positive charges and weakens the interaction of DNA and histone.
D. The acetylation and methylation site of histone can be used to recruit the chromatin remodeling complex, which would affect the interaction of DNA and histone.

DNA fragment included in a nucleosome core particle is:____

A. 55bp
B. 146bp
C. 166bp
D. 200bp

Which of the following is NOT included in the histone core octamer of nucleosome:____

A. H1
B. H2A
C. H3
D. H4
E. H2B

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