Not all second messengers are water-soluble and diffuse freely through the cytosol.
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Disulfide Bonds Are Formed only in the lumen of the rough ER
Dynamin Is Required for Pinching Off of Clathrin Vesicles
Improperly Folded Proteins Are Exported from the ER and Degraded in the lysosome
The ABC Cystic Fibrosis Transmembrane Regulator (CFTR) Is a Chloride Channel, Not a Pump