题目内容

水杨酰胺在人体中的主要代谢反应是首先经胃肠道黏膜中的硫酸结合,然后在肝脏内与葡萄糖醛酸的结合反应。当剂量增加时,胃肠道内硫酸结合物的生成率逐渐降低,而此时由肝脏内葡萄糖醛酸结合物的生成率却升高,其原因是

A. 剂量增加时,硫酸结合反应达到饱和,而葡萄糖醛酸结合反应却不易达到饱和
B. 剂量增加时,葡萄糖醛酸结合反应达到饱和,而硫酸结合反应却不易达到饱和
C. 剂量增加时,硫酸结合反应达到饱和
D. 剂量增加时,葡萄糖醛酸结合反应达到饱和
E. 给药途径的影响

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A. 分散片
B. 在胃中漂浮的胃漂浮片
C. 在十二直肠快速释放的肠溶性泡腾片
D. 缓释片
E. 速释片

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