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Select the statement below that best summarizes the overall opinion of the authors with respect to the role of vitamin and mineral supplements in the prevention of chronic disease?

A. So far the evidence has shown vitamin and mineral supplements are harmful or ineffective for chronic disease prevention. However, they should not be avoided until further large prevention trials are conducted.
B. More research is recommended but until new trials are completed the use of vitamin and mineral supplements has clear benefits and is justified for the general population.
C. The use of vitamin and mineral supplement has no clear benefit and in some cases possible harm. It is not justified for the general population, who show no clear evidence of micronutrient deficiencies, to take these types of supplements.

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c) Lamas and associates (paragraph 3)TACT (Trial to Assess Chelation Therapy): Oral High-Dose Multivitamins and Minerals after Myocardial Infarction

A. Case control study
B. Cohort study
C. Interventional study
D. Meta-analysis

b) Grodstein and coworkers (paragraph 2)Long-Term Multivitamin Supplementation and Cognitive Function in Men

A. Case control study
B. Cohort study
C. Interventional study
D. Meta-analysis

a) Fortmann and colleagues (paragraph 1)Vitamin and Mineral Supplements in the Primary Prevention of Cardiovascular Disease and Cancer: An Updated Systematic Evidence Review for the U.S. Preventive Services Task Force

A. Case control study
B. Cohort study
C. Interventional study
D. Meta-analysis

The reason that progestins are added to estrogen supplements is:

A. to make the estrogen more soluble
B. to reduce the risk of uterine cancer
C. to reduce the risk of breast cancer
D. to make the tablets less bitter
E. to further decrease bone loss

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