多选题 Which of the following damages can be repaired by nucleotide excision repair system:()
A. The broken of DNA double strands
Base insertion
C. Alkylation of bases
D. The formation of thymine dimer
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Mismatch repair is based on recognition of the mismatched base during replication. Which of the following is correct about this:()
A. UvrABC system recognizes the mismatched bases and add the correct one with the help of DNA polymerase
B. If recognition happens before methylation of DNA parental strand, the sequence of repair tends to be wild type.
C. Mismatch site is usually repaired by single-strand exchange.
D. Mismatch repair relies on the repairing function which is repressed under normal conditions by the protein LexA.
Among the responses of cells to DNA damage, which is most likely to lead to high mutation rate:()
A. Photoreactivation repair
Base excision repair
C. Recombination repair
Damage-removing synthesis
Four steps are involved in most of DNA repairs. The correct order of the four steps is:()
A. recognition、excision、re-synthesis、re-ligation
B. re-ligation、re-synthesis、excision、recognition
C. excision、re-synthesis、re-ligation、recognition
D. recognition、re-synthesis、re-ligation、excision
In photoreactivation repair, which of the following enzyme binds to pyrimidine dimer?()
A. Photolyase
B. Exonuclease
C. Endonuclease
D. Ligase
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