Which statement below is correct about DNA-damage checkpoint?()
A. Its function results in degradation of cyclin.
B. It can only detect single-strand DNA damage.
C. ATM is responsible for detecting double-strand DNA damage.
D. It may block the expression of cyclin
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If cell’s chromosomes is not well segregated, cell cycle will be halted at()
A. S
B. G2
C. M
D. G1
Which of the following statements describes the primary function of the unreplicated-DNA checkpoint ? ()
A. It checks whether the mitotic spindle has formed.
B. It determines if the mitotic spindle has broken down.
C. It ensures that chromosomes are aligned at the metaphase plate and and captured by microtubules from opposing spindle poles.
D. It verifies that all DNA has been fully duplicated
Gene coding for P53 is a type of ()
A. kinase inhibitor.
B. tumor suppressor gene.
C. proto-oncogene.
D. oncogene.
A gene that codes for an negative cell-cycle regulator is called a ()
A. kinase inhibitor.
B. tumor suppressor gene.
C. proto-oncogene.
D. oncogene.
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