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Proteins in signaling pathways use a variety of binding domains to assemble into signaling complexes. If matching the following domains with their binding targets,Which one is correct? a. PH domain 1. phosphorylated tyrosines b. PTB domain 2. proline-rich sequences c. SH2 domain 3. phosphorylated inositol phospholipids d. SH3 dom

A. a and 1
B. b and 2
C. c and 3
D. d and 3

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All of the following statements describe nuclear transport are true except:

A. When Ran-GTP binds to Importin-Cargo (NLS) complex, it promotes its disassembly.
B. When Ran-GTP binds to Exportin-Cargo (NES) complex, it promotes its assembly.
C. Localization of Ran-GAP in the nucleus and Ran-GEF in the cytoplasm is necessary for unidirectional transport of cargo proteins containing an NES.
D. Ran-GTP has high affinity for cargo proteins containing either NLS or NES inside nucleus.

Asymmetry in the structure of the plasma membrane is reflected in

A. differences in the lipid composition on the inner and outler leaflets of the bilayer
B. presence of carbohydrate attached to lipid and protein on the outer surface but not the inner
C. presence of specific kinds of lipid-anchored proteins only on the cytoplasmic surface of the
D. all of the above

In cells, the g-tubulin ring complex is found

A. in the hollow core of the microtubule
B. at the microtubule (−) end.
C. at the microtubule (+) end.
D. along the outer wall of the microtubule.

All of the following statements describe Kinesin I are true except:

A. Kinesin I is a (−) end-directed motor
B. Kinesin I transports vesicles along microtubules
C. Kinesin I binds and hydrolyzes ATP to produce movement
D. Kinesin I is composed of two heavy chains and two light chains

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