题目内容
In Phase ____ trials, researchers test a drug or treatment in a small group of people (20–80) for the first time. The purpose is to study the drug or treatment to learn about safety and identify side effects.
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Greek physician Hippocrates (460–377 BCE) is widely recognized as the father of ________________, due to his careful attention to observation and his commitment to explaining diseases as resulting from natural, rather than supernatural, causes.
On May 14, ______, English surgeon Edward Jenner (1749–1823) inoculated James Phipps, an eight-year-old boy, with fluid from a cowpox pustule to determine whether this would prevent him from developing smallpox. Jenner had observed that dairymaids exposed to cowpox seemed to have resistance to smallpox, and hypothesized that exposure to cowpox would provide protection against smallpox.
_________ chemist and microbiologist Louis Pasteur (1822–1896), who developed the germ theory of disease, also tested experimental vaccines on human subjects.
In 1885,Louis Pasteur (1822–1896) gave an experimental _______ vaccine to a nine-year old boy, Joseph Meister, without first testing the vaccine on animals. Meister had been mauled by a dog, and Pasteur gave the boy the vaccine in the hope of preventing the disease. The vaccine worked, and other parents asked Pasteur to administer it to their children.
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