In the following motifs of transcription factors, which can help the dimerization of transcription factor:()
A. Zif
B. Leucine zipper
C. BHLH
D. HTH
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which domain can be found in transcription factor:()
A. DNA binding domain
B. Transactivation domain
C. Dimerization domain
D. Nuclear localization sequence or nuclear export sequence
E. Ligand binding domain
Which is NOT true about the transcription factor with Zinc finger structure:()
A. It usually contains multiple zinc finger arrangement.
B. About 23 amino acids form a zinc finger.
C. Two cysteines and two histidines in the structure are responsible for the combination of Zinc.
D. One side of the zinc finger is connected with major groove of DNA by forming beta folding.
Which is NOT the mechanism of the activating transcription factors:()
A. Combined with general transcription factors to promote the assembly of transcription initiation complex
B. Changing protein conformation to activate the enzyme in basal apparatus.
C. Recruiting chromatin modification complex to change chromatin morphology.
D. Generation of accessible and free DNA by chromatin remodeling.
Activator protein 1 (AP-1) consists of c-jun protein and c-fos proteins. The type of protein motif that make it bind to DNA is:()
A. Leucine zipper
B. HLH
C. HTH
D. Zif
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