Q2 – Among the following techniques for the detection of bacterial resistance, which one is currently the best for antibiotic treatment choice?
A. 1 - Antibiotic susceptibility testing.
B. 2 - Enzymatic activity detection.
C. 3 - Immunological techniques.
D. 4 - Gene detection.
E. 5 - Whole-genome sequencing.
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Q3 – Among the following options on Whole Genome Sequencing (WGS) which one is correct?
A. 1 - It determines the DNA sequence of an entire bacterial genome.
B. 2 - It detects expressed genes only.
C. 3 - It is fast.
Q4 – How to predict the resistance phenotype from the genome sequence?
A. 1 - By identifying antibiotic resistance genes.
B. 2 - By identifying point mutations in specific genes.
C. 3 - By using a learning set of isolates for the species with known genome sequence and antibiotic resistance phenotypes.
Q5 – What is not directly predicted by genome sequencing?
A. 1 - The presence of an antibiotic resistance gene.
B. 2 - Its integrity.
C. 3 - Its expression.
Q6 - Among the following options about antibiotic susceptibility testing, which one is correct?
A. 1 - Guidelines are essential to determine the categorization in Susceptible / Intermediate / Resistant.
B. 2 - Minimum Inhibition Concentration should not be used to adapt the antibiotic posology.
C. 3 - Macro dilution methods are widely used to perform antibiotic susceptibility testing.