Which is the maximum UV absorption wavelength of nucleic acids:____
A. 280nm
B. 260nm
C. 240nm
D. 220nm
E. 490nm
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Which of the following DNA molecule has a relatively higher Tm value?____
A. 5’-ATATCATATGATATGTA-3’
B. 5’-CGGTACTCGTGCAGGT-3’
The hybridization of nucleic acid could happen between DNA and RNA, DNA and DNA, then, which of the following RNA sequence could hybridize with single strand DNA with sequence 5’-CGGTA-3’:____
A. 5’-UACCG-3’
B. 5’-GCCAU-3’
C. 5’-GCCUU-3’
D. 5’-AUCCG-3’
E. 5’-UAGGC-3’
A circular DNA with B form reduces its crossing number by 1 with the help of topoisomerase I, then which the following is false:____
A. The linking number of this DNA is reduced by 1.
B. No ATP is consumed in this process.
C. This DNA can maintain its relaxed B form.
D. A negatively supercoiled DNA would be formed if it maintains its relaxed B form.
E. The twisting number of DNA would be keep the same if it maintains its relaxed B form.
Which the following is correct about the topoisomerase II:____
A. It can break the glycosidic bond in DNA double strands.
B. It doesn’t consume ATP when it works.
C. It can increase the number of negatively supercoiled DNA.
D. It can stabilize the topological structure of DNA molecule.
E. It makes positive supercoiled DNA.
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