All formulas in Chinese medicine contain the full hierarchy of ingredients, namely, the chief, the deputy, the assistant and the envoy.
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Ephedrae Herba (Ma Huang) belongs to astringent medicinal and Rhei Radix et Rhizoma (Da Huang) is a kind of purgative medicinal.
The ingredient that is directed against, and has the greatest effect upon, the principal pattern or disease is called the chief or the monarch medicinal.
The quality and curative effect of certain Chinese medicinal has nothing to do with its place of production.
The deputy or minister medicinal has only one function, that is to aid the chief ingredient in treating the principal pattern or disease.