Acetyl chloride undergoes nucleophilic substitution at a faster rate than methyl acetate because ________.()
A. the ester is more sterically hindered than the acid chloride
B. the acid chloride is more sterically hindered than the ester
C. the methoxide is a better leaving group than chloride
D. esters hydrolyze faster than acid chlorides
E. chloride is a better leaving group than methoxide
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Typically, amides will hydrolyze under ________ conditions than esters.()
A. milder
B. more dilute
C. more vigorous
D. less vigorous
E. more saline
Esters and amides are most easily made by nucleophilic acyl substitution reactions on ________.()
A. alcohols
B. acid anhydrides
C. carboxylates
D. carboxylic acids
E. acid chlorides
Which of the following is/are formed in the reaction between ethyl butanoate and ethyl amine? ()
A. ethanol
B. 1-butanol
C. N-ethylbutanamide
D. both A and C
E. both B and C
Which of the following esters undergoes hydrolysis in base most easily?()
A. CH3CH2CO2CH3
B. (CH3)2CHCH2CO2CH3
C6H5O2CCH3
D. p-CH3C6H4O2CCH3
E. p-NO2C6H4O2CCH3
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