Which of the following description is correct about the poly(A) tail of mRNA in eukaryotes:
A. It is added after mRNA is transported into cytoplasm.
B. It is added by protein CPSF and CstF.
C. It can be added on the 3’-OH of primary transcription product.
D. It is transcripted from the poly(T) of template DNA.
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1.Which is the following description about the carboxyl-terminal domain (CTD) in RNA polymerase II is NOT correct:
A. It binds to the mediator complex.
B. Its phosphorylation is related to the kinase activity of TFIIB.
C. The lack of CTD domain of RNA pol II would make the transcription not able to initiate.
D. The phosphorylation of its S5 site makes the change from initial polymerase form to elongation polymerase form.
E. The phosphorylation of its specific site will recruit many factors for RNA splicing and transcriptional termination.
Which of the following statement about TBP protein is correct:
A. TBP could induce the bending of DNA double helix.
B. TBP can interacted with DNA major groove.
C. TBP can bind to different TAFs in different promoters.
D. TBP participates in the transcription initiation process catalyzed by three RNA polymerases in eukaryotic cells.
Which of the following is cis-element:
A. TATA Box
B. HMT
Co-activator
D. HDAC
Enhancer
9.Which of the following is cis-element:
A. TATA Box
B. HMT
Co-activator
D. HDAC
Enhancer
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