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Whether the cause is maternal anti-bodies, heavy metals or something else, there is no question that the brains of young children with autism have unusual features. To begin with, they tend to be too big. In studies based on magnetic resonance imaging(MRI)and basic tape-measure readings , neuroscientist Eric Courchesne at Children" s Hospital of San Diego showed that while children with autism are born with ordinary-size brains, they experience a rapid expansion by age 2—particularly in the frontal lobes. By age 4, says Courchesne, autistic children tend to have brains the size of a normal 13-year-old. More recent studies by Admiral and others have found that the amygdale, an area associated with social behavior, is also oversize, a finding Admiral believes is related to the high levels of anxiety seen in as many as 80% of people with autism. Harvard pediatric neurologist Dr. Martha Herbert reported last year that the excess white matter in autistic brains has a specific distribution; local areas tend to be over connected, while links between more distant regions of the brain are weak. The brain" s right and left hemispheres are also poorly connected. It" s as if there are too many competing local services but no long distance. This observationjibesneady with imagining studies that look at live brain activity in autistic people. Studies using functional MRI show a lack of coordination among brain regions, says Marcel Just, director of Carnegie Mellon" s Center for Cognitive Brain Imaging in Pittsburgh, Pa. Just has scanned dozens of 15-to-35-year-old autistic people with IQs in the normal range, giving them thinking tasks as he monitors their brain activity. " One thing you see," says Just, " is that activity in different areas is not going up and down at the same time. There" s a lack of synchronization, sort of like a difference between a jam session and a string quartet. In autism, each area does its own thing. " What remains unclear is whether the interconnectivity problem is the result of autism or its cause. "It" s impossible to tell the chicken from the egg at this point," Just says. Autistic people have been shown to use their brains in unusual ways; they memorize alphabet characters in apart of the brain that ordinarily processes shapes. They tend to use the visual centers in the back of the brain for tasks usually handled by the prefrontal cortex. They often look at the mouth instead of the eyes of someone who is speaking. Their focus, says psychologist Ami Klin of Yale" s Child Study Center, is " not on the social allegiances—for example, the longing gaze of a mother—but physical allegiances—a mouth that moves. " Which is one of the characteristics of the autistic brain
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Most patients respond to the awareness that they have a terminal illness with the statement, "Oh no, this can"t happen to me. " After the first shock, numbness, and need to deny the reality of the situation, the patient begins to send out cues that he is ready to "talk about it". If we, at that point, need to deny the reality of the situation, the patient will often feel deserted, isolated, and lonely and unable to communicate with another human being what he needs so desperately to share. Most patients who have passed the stage will become angry as they ask the question, "Why me" Many look at others in their environment and express envy, jealousy, anger, and rage toward those who are young, healthy, and full of life. These are the patients who make life difficult for nurses, physicians, social workers, clergymen, and members of their families. Without justification they criticize everyone. What we have to learn is that the stage in terminal illness is a blessing, not a cure. These patients are not angry at their families or at the members of the helping professions. Rather, they are angry at what these people represent; health and energy. Without being judgmental, we must allow these patients to express their anger and dismay. We must try to understand that the patients have to ask, "Why me" and that there is no need on our part to answer this question concretely. Once a patient has ventilated his rage and his envy, then he can arrive at the bargaining stage. During this time, he" s usually able to say, "Yes, it is happening to me—but". The"but" usually includes a prayer to God; "If you give me one more year to live, I will be a good Christian. " The first stage of most patients facing death is the stage of______.
Researchers have recently found a connection between disease and stressful situations. To test this theory, psychologists are trying to find a link between the brain and the immune system. The immune system in our bodies fights the bacteria and viruses which cause disease. Therefore , whether or not we are likely to get various diseases depends on how well our immune system works. Biologists used to think that the immune system was a separate, independent part of our bodies. Recently, however, they have found that our brain can affect our immune system. This discovery indicates that there may be a connection between emotional factors, such as stress or depression, and illness. Although many doctors in the past suspected a connection between emotional factor and disease, they had no proof. Scientists have only recently discovered how the brain and the immune system function. Before this, no one could see a link between them. As a result, medical science never seriously considered the idea that psychological factors could cause disease. Several recent studies showed a connection between stress and illness, for example, researchers went to an American military school to study the students. They found that the sick students there had a lot of academic pressure and wanted to achieve, but they were not very good students. In a similar study, researchers studied a group of student nurses and found that the nurses who developed cold sores were the ones who described themselves as generally unhappy people. In addition to these results, which support their theory, researchers are also looking for proof that stress can damage the immune system. Researchers studied recently bereaved people, i. e. , people whose loved ones have just died, because they are more likely to become ill or die. By examining the immune system of recently bereaved people, the researchers made an important discovery. They examined some white blood cells which are an important part of the immune system. They were not functioning properly. The fact that they were not working correctly indicates that severe psychological stress, such as a loved one" s death, may damage an important part of our immune system. There is still no positive proof of a connection between the immune system and psychological factors. Researchers also say that the results of the studies on bereaved people could have a different explanation. For example, bereaved people often sleep and eat less than normal, or may drink alcohol or take medication. These factors can also affect the immune system. More research is needed to clearly establish the connection between the immune system and psychological factors. The study on the military school students indicated that______.
Whether the cause is maternal anti-bodies, heavy metals or something else, there is no question that the brains of young children with autism have unusual features. To begin with, they tend to be too big. In studies based on magnetic resonance imaging(MRI)and basic tape-measure readings , neuroscientist Eric Courchesne at Children" s Hospital of San Diego showed that while children with autism are born with ordinary-size brains, they experience a rapid expansion by age 2—particularly in the frontal lobes. By age 4, says Courchesne, autistic children tend to have brains the size of a normal 13-year-old. More recent studies by Admiral and others have found that the amygdale, an area associated with social behavior, is also oversize, a finding Admiral believes is related to the high levels of anxiety seen in as many as 80% of people with autism. Harvard pediatric neurologist Dr. Martha Herbert reported last year that the excess white matter in autistic brains has a specific distribution; local areas tend to be over connected, while links between more distant regions of the brain are weak. The brain" s right and left hemispheres are also poorly connected. It" s as if there are too many competing local services but no long distance. This observationjibesneady with imagining studies that look at live brain activity in autistic people. Studies using functional MRI show a lack of coordination among brain regions, says Marcel Just, director of Carnegie Mellon" s Center for Cognitive Brain Imaging in Pittsburgh, Pa. Just has scanned dozens of 15-to-35-year-old autistic people with IQs in the normal range, giving them thinking tasks as he monitors their brain activity. " One thing you see," says Just, " is that activity in different areas is not going up and down at the same time. There" s a lack of synchronization, sort of like a difference between a jam session and a string quartet. In autism, each area does its own thing. " What remains unclear is whether the interconnectivity problem is the result of autism or its cause. "It" s impossible to tell the chicken from the egg at this point," Just says. Autistic people have been shown to use their brains in unusual ways; they memorize alphabet characters in apart of the brain that ordinarily processes shapes. They tend to use the visual centers in the back of the brain for tasks usually handled by the prefrontal cortex. They often look at the mouth instead of the eyes of someone who is speaking. Their focus, says psychologist Ami Klin of Yale" s Child Study Center, is " not on the social allegiances—for example, the longing gaze of a mother—but physical allegiances—a mouth that moves. " Which part is related to human anxiety
Researchers have done extensive studies of how well childrencomply withtheir teachers" instructions.
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