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A 22-year-old woman has a congenital anemia that has required multiple transfusions of RBCs for many years. On physical examination, she now has no significant findings; however, liver function tests show reduced serum albumin. Which of the following findings would most likely appear in a liver biopsy specimen. _ _

A. Steatosis in hepatocytes
Bilirubin in canaliculi
C. Glycogen in hepatocytes
D. Amyloid in portal triads
E. Hemosiderin in hepatocytes

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A 50-year-old man experienced an episode of chest pain 6 hours before his death. A histologic section of left ventricular myocardium taken at autopsy showed a deeply eosinophilic-staining area with loss of nuclei and cross-striations in myocardial fibers. There was no hemorrhage or inflammation. Which of the following conditions most likely produced these myocardial changes. _ _

A. Viral infection
B. Coronary artery thrombosis
C. Blunt chest trauma
D. Antibodies directed against myocardium
E. Protein-deficient diet

A 69-year-old man has had difficulty with urination, including hesitancy and frequency, for the past 5 years. A digital rectal examination reveals that the prostate gland is palpably enlarged to about twice normal size. A transurethral resection of the prostate is performed, and the microscopic appearance of the prostate “chips” obtained is that of nodules of glands with intervening stroma. Which of the following pathologic processes has most likely occurred in the prostate. _ _

Apoptosis
B. Dysplasia
C. Fatty change
D. Hyperplasia
E. Hypertrophy
F. Metaplasia

The key difference of pathological change between acute fulminant hepatitis and subacute fulminant hepatitis is__

A. shrunken liver with wrinkled capsules
B. regeneration of hepatocytes
C. inflammatory cells exudation
D. liver cell necrosis
E. Local liver cancer

Neutrophil-rich acute suppurative inflammation is common in the_ _

A. chronic infections
B. “pyogenic” bacterial infections
C. actue viral infections
D. mycobacterium tuberculosis infection
E. skin cancer

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