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Japan is an unusual mixture of traditional and ultra-modern. This can be confusing for the visitor because, although it looks quite western, Japan is still in many ways very oriental. Whenever you go into a house you must take off your shoes. Sometimes your host will provide you with slippers; if not, you walk round in your socks. A visitor should also expect in more traditional houses, hotels and restaurants to eat kneeling down on the floor on a cushion in front of a low table. It is a good idea to get used to eating with chopsticks but, if you can’t manage, ask for a knife and fork. The Japanese are extremely polite and friendly: you can nearly always find someone who speaks English. In summer the country is very hot and humid so anyone planning a trip then ought to take light, comfortable clothes with them. The majority of tourists head for Tokyo but you ought not to miss the chance of visiting the old capital cities of Kyoto and Nara. From Tokyo you can get to Kyoto in three hours on the "Shinkansen" superexpress. If you are driving, it is important to remember that in Japan you have to drive on the left-hand side of the road. What is the traditional way to sit for a mealWhen having a meal, people______.
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The Language Learning Theory course is an option during the third semester of your program. It is an introduction to aspects of Psycholinguistics and Second Language Acquisition Research. The course will deal specifically with those aspects of recent research that are relevant to the comprehension and production of spoken language. Most of the course will, in other words, be spent considering the processes involved in understanding and producing spoken language. At each stage, we shall be relating the implications of recent research and theories to the practice of foreign language teaching. The course aims to provide relevant background for all language teachers who are interested in WHY and HOW current teaching approaches have been developed. The course will be held during the first ten weeks of this semester from 8: 30 to 10: 30 on Tuesday mornings. A handout giving an outline of the topics of each of the ten sessions is available for those who wish to consider the course in more detail. The course will be principally conducted through lecture and seminar. Learners will, at times, be asked to take part in small language experiments. Handouts and worksheets will be distributed each week. Preparatory reading and follow-up reading will be required for each session. Learners’ participation in class activities will be taken into consideration. Attendance at classes is essential. There will be four short, assessed assignments during the course. Participation in classes will account for 10% of the final mark. Assignments will account for 60%. The remaining 30% is for the final test—which will be held one week after the end of the course. You may collect the handout (covering the information I have given you today) from me at the end of this session. If you need further details, you are welcome to ask me personally or see the secretary in Room 513. The course code is LLT 96. Students who are interested in______are most UNLIKELY to take this course
Testing TimesResearchers are working on ways to reduce the need for animal experiments, but new laws may increase the number of experiments needed. The current situation In an ideal world, people would not perform experiments on animals. For the people, they are expensive. For the animals, they are stressful and often painful. That ideal world, sadly, is still some way away. People need new drugs and vaccines. They want protection from the toxicity of chemicals. The search for basic scientific answers goes on. Indeed, the European Commission is forging ahead with proposals that will increase the number of animal experiments carried out in the European Union, by requiring toxicity tests on every chemical approved for use within the union’s borders in the past 25 years. Already, the commission has identified 140,000 chemicals that have not yet been tested. It wants 30,000 of these to be examined right away, and plans to spend between ~ 4 billion — 8 billion ($5 billion—10 billion) doing so. The number of animals used for toxicity testing in Europe will thus, experts reckon, quintuple (翻五倍) from just over lm a year to about 5m, unless they are saved by some dramatic advances in non-animal testing technology. At the moment, roughly 10% of European animal tests are for general toxicity, 35% for basic research, 45% for drugs and vaccines, and the remaining 10% a variety of uses such as diagnosing diseases. Animal experimentation will therefore be around for some time yet. But the search for substitutes continues, and last weekend the Middle European Society for Alternative Methods to Animal Testing met in Linz, Austria, to review progress. A good place to start finding alternatives for toxicity tests is the liver--the organ responsible for breaking toxic chemicals down into safer molecules that can then be excreted. Two firms, one large and one small, told the meeting how they were using human liver cells removed incidentally during surgery to test various substances for long-term toxic effects. One way out of the problem PrimeCyte, the small firm, grows its cells in cultures over a few weeks and doses them regularly with the substance under investigation. The characteristics of the cells are carefully monitored, to look for changes in their microanatomy. Pfizer, the big firm, also doses its cultures regularly, but rather than studying individual cells in detail, it counts cell numbers. If the number of cells in a culture changes after a sample is added, that suggests the chemical in question is bad for the liver. In principle, these techniques could be applied to any chemical. In practice, drugs (and, in the case of PrimeCyte, food supplements) are top of the list. But that might change if the commission has its way: those 140,000 screenings look like a lucrative market, although nobody knows whether the new tests will be ready for use by 2009, when the commission proposes that testing should start. Other tissues, too, can be tested independently of animals. Epithelix, a small firm in Geneva, has developed an artificial version of the lining of the lungs. According to Huang Song, one of Epithelix’s researchers, the firm’s cultured cells have similar microanatomy to those found in natural lung linings, and respond in the same way to various chemical messengers. Dr. Huang says that they could be used in long-term toxicity tests of airborne chemicals and could also help identify treatments for lung diseases. The immune system can be mimicked and tested, too. ProBioGen, a company based in Berlin, is developing an artificial human lymph node (淋巴结) which, it reckons, could have prevented the neardisastrous consequences of a drag trial held in Britain three months ago, in which (despite the drag having passed animal tests) six men suffered multiple organ failure and nearly died. The drug the men were given made their immune systems hyperactive. Such a response would, the firm’s scientists reckon, nave teen identified by their lymph node, which is made from cells that provoke the immune system into a response. ProBioGen’s lymph node could thus work better than animal testing.A second alternative Another way of cutting the number of animal experiments would be to change the way that vaccines are tested, according to Coenraad Hendriksen of the Netherlands Vaccine Institute. At the moment, all batches of vaccine are subject to the same battery of tests. Dr. Hendriksen argues that this is over-rigorous. When new vaccine cultures are made, belt-and-braces tests obviously need to be applied. But if a batch of vaccine is derived from an existing culture, he suggests that it need be tested only to make sure it is identical to the batch from which it is derived. That would require fewer test animals. All this suggests that though there is still some way to go before drugs, vaccines and other substances can be tested routinely on cells rather than live animals, useful progress is being made. What is harder to see is how the use of animals might be banished from fundamental research. Weighing the balance In basic scientific research, where the object is to understand how, say, the brain works rather than to develop a drug to treat brain disease, the whole animal is often necessarily the object of study. Indeed, in some cases, scientific advances are making animal tests more valuable, rather than less. Geneticmodification techniques mean that mice and rats can be remodelled to make them exhibit illnesses that they would not normally suffer from. Also, genes for human proteins can be added to them, so that animal tests will more closely mimic human responses. This offers the opportunity to understand human diseases better, and to screen treatments before human trials begin. However, the very creation of these mutants (突变异种) counts as an animal experiment in its own right, so the number of experiments is increasing once again. What is bad news for rodents, though, could be good news for primates. Apes and monkeys belong to the same group of mammals as humans, and are thus seen as the best subjects for certain sorts of experiment. To the extent that rodents can be "humanised", the number of primate experiments might be reduced. Some people, of course, would like to see them eliminated altogether, regardless of the effect on useful research. On June 6th the British Union for the Abolition of Vivisection, an animal-rights group, called for the use of primates in research to be banned. For great apes, this has already happened. Britain, Austria, the Netherlands, New Zealand and Sweden have ended experiments on chimpanzees, gorillas, bonobos and orang-utans. Experiments on monkeys, though, are still permitted. And some countries have not banned experiments on apes. In America, for example, about 1,000 chimpanzees a year are used in research. This is a difficult area. Great apes are man’s closest relatives, having parted company from the human family tree only a few million years ago. Hence it can be (and is) argued that they are indispensable for certain sorts of research. On the other hand, a recent study by Andrew Knight and his colleagues at Animal Consultants International, an animal-advocacy group, casts doubt on the claim that apes are used only for work of vital importance to humanity. Important papers tend to get cited as references in subsequent studies, so Mr. Knight looked into the number of citations received by 749 scientific papers published as a result of invasive experiments on captive chimpanzees. Half had received not a single citation up to ten years after their original publication. That is damning. Animal experiments are needed for the advance of medical science, not to mention people’s safety. But if scientists are to keep the sympathy of the public, they need to do better than that. PrimeCyte and Pfizer began to find alternatives to animal testing because they were advocates of animal protection.
Questions 23 to 25 are based on the conversation you have just heard.
The Language Learning Theory course is an option during the third semester of your program. It is an introduction to aspects of Psycholinguistics and Second Language Acquisition Research. The course will deal specifically with those aspects of recent research that are relevant to the comprehension and production of spoken language. Most of the course will, in other words, be spent considering the processes involved in understanding and producing spoken language. At each stage, we shall be relating the implications of recent research and theories to the practice of foreign language teaching. The course aims to provide relevant background for all language teachers who are interested in WHY and HOW current teaching approaches have been developed. The course will be held during the first ten weeks of this semester from 8: 30 to 10: 30 on Tuesday mornings. A handout giving an outline of the topics of each of the ten sessions is available for those who wish to consider the course in more detail. The course will be principally conducted through lecture and seminar. Learners will, at times, be asked to take part in small language experiments. Handouts and worksheets will be distributed each week. Preparatory reading and follow-up reading will be required for each session. Learners’ participation in class activities will be taken into consideration. Attendance at classes is essential. There will be four short, assessed assignments during the course. Participation in classes will account for 10% of the final mark. Assignments will account for 60%. The remaining 30% is for the final test—which will be held one week after the end of the course. You may collect the handout (covering the information I have given you today) from me at the end of this session. If you need further details, you are welcome to ask me personally or see the secretary in Room 513. The course code is LLT 96. According to the passage, when will the final test of the course be given
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