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正常成人一次失血1000mL时（）。
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采用（ 43）设计模式可保证一个类仅有一个实例：采用（ 44）设计模式可将组合成树形结构以表示“部分 -整体”的层次结构，使用户对单个对象和组合对象的使用具有一致性；采用（ 45）设计模式可动态地给一个对象添加一些额外的职责。 （44）处填（）。
疟脉自弦，______者多热，______者多寒。
Until recently most historians spoke very critically of the Industrial Revolution. They ______ that in the long run industrialization greatly raised the standard of living for the _______ man. But they insisted that its ______ results during the period from 1750 to 1850 were widespread poverty and misery for the _______of the English population. _______ contrast, they saw in the preceding hundred years from 1650-1750, when England was still a _______ agricultural country, a period of great abundance and prosperity. This view, _____ , is generally thought to be wrong. Specialists _______ history and economics, have ______ two things: that the period from 1650 to 1750 was _______ by great poverty, and that industrialization certainly did not worsen and may have actually improved the conditions for the majority of the populace (平民).
Question 45-48 The horse preceded man on earth. Although the earliest remains of primitive horses have been found on the North American continent, many scientist believe this small species traveled over a land mass in the Bering Sea to found the beginnings of the modern horse in Asia. It became extinct in America. Other scientists believe that the horse may have originated in Asia. In any event the animal soon spread into China, Europe, and the Middle East. The first modern horses to be introduced into the American continent came with the early Spanish explorers. Horses were bred into many types. The heavy horses developed in the low countries of Europe and were used for Arabian. The only true wild horses left in the 20th century are found in Mongolia. Horses are said to rate in intelligence after the ape, elephant, and dog. They have excellent memories and can sometimes find their way home when lost, and sense danger better that their masters. The early civilizations of man that had made use of ht horse developed more rapidly than those which did not. The horse originated___________
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