All of the following reasons are L-DOPA can be used in treatment of Parkinson’s disease for EXCEPT: ( )
A. It can cross the blood brain barrier and dopamine can not
B. It is the metabolic precursor of dopamine
C. L-DOPA is rapidly metabolized to dopamine by DOPA decarboxylase
D. L-DOPA is very effective on reducing all the signs and symptoms of PD
E. dopamine is toxic
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What is NOT potential target to inhibit platelet aggregation and activation? ( )
ADP receptor
B. Fibrinogen cleavage
C. Glycoprotein IIb/IIIa
D. Cyclooxygenase
E. TXA2 production
Which glucocorticoid is not suitable for patients with liver disease?( )
A. Dexamethasone
B. Methylprednisolone
C. Fludrocortisone
D. Hydrocortisone
E. Prednisone
Which of the following is not true for Thioamides? ( )
A. Takes weeks to have effects
B. Inhibits the process of iodination
C. Inhibits the coupling of mono-iodotyrosine or di-iodotyrosine
D. Inhibits the uptake of iodide from circulation into thyroid
E. Inhibits the conversion of thyroxine (T4) into tri-iodothyronine (T3)
Which of the following is true? ( )
A. Insulin lispro has longer onset than regular insulin
B. The anti-inflammation effect of glucocorticoids is mainly through transcription regulation
C. The adverse effects of thiazolidinediones usually involves gastrointestinal problems
D. The mechanism and cautions of iodides and radioactive iodine are similar
E. Cortisol are released in response of stress, so glucocorticoids are good for mental health
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